Barcelona stumbled for a third straight match in its quest to defend its Spanish league title after losing at Real Sociedad 1-0 on Saturday, letting Atletico Madrid and Real Madrid tighten the race even further.
Bayern Munich ground out a 3-1 win at Stuttgart and provisionally opened an eight-point lead to move closer to an unprecedented fourth straight Bundesliga title on Saturday.
Juventus moved provisionally nine points clear at the top of Serie A as it came from behind to beat fierce rival AC Milan 2-1 on Saturday.
Lyon moved above Monaco and into second spot and automatic qualification for the Champions League with a 2-0 win at Montpellier on Friday.
Liverpool claimed an excellent 1-1 draw with Borussia Dortmund in the first leg of their Europa League quarterfinal on Thursday as Jurgen Klopp made an emotional return to the Westfalenstadion.
Defending champion Guangzhou Evergrande is on the brink of a group-stage exit in the Asian Champions League after a 1-0 loss to Urawa Reds on Tuesday left the big-spending Chinese club winless in four games.
Matias Laba was shown a straight red card in the first half, but the Vancouver Whitecaps still held on for a 0-0 tie with the Los Angeles Galaxy on Saturday night.
English Premier League soccer players were among 150 sports stars who were prescribed banned performance-enhancing drugs, a British doctor claimed in an expose by The Sunday Times newspaper.
Franck Ribery's spectacular volley sparked Bundesliga leader Bayern Munich over Eintracht Frankfurt 1-0, and three substitutes helped Borussia Dortmund keep pace by beating Werder Bremen 3-2 on Saturday.
Juventus moved provisionally six points clear at the top of Serie A after beating Empoli 1-0 on Saturday.