Diego Costa ended a seven-game goal drought in style to help Chelsea open up a seven-point lead in the Premier League with a 4-2 victory over Southampton on Tuesday.
Atletico Madrid's 11-game unbeaten streak came to an end on Tuesday after it squandered a series of chances and then conceded a late goal to lose 1-0 at home to Villarreal in the Spanish league.
Roma boosted its bid for second place in Serie A and automatic entry into the Champions League with a 4-1 win at Pescara, which was mathematically relegated on Monday.
Arkadiusz Milik scored his first goal since his lengthy injury layoff but it wasn't enough to prevent Napoli from drawing 2-2 at Sassuolo on Sunday and missing the chance to move second in Serie A.
Cyle Larin scored twice to help Orlando City coach Jason Kreis notch a win against his former team, beating New York City 2-1 on Sunday to move atop the Eastern Conference standings.
Eden Hazard had a rare view from the Chelsea bench, and it wasn't comfortable viewing.
Bayern Munich was held for a second successive Bundesliga game, with the leader twice coming from behind against lowly Mainz to recover a 2-2 draw on Saturday.
Barcelona has decided to leave Neymar out of the decisive "clasico" against Real Madrid because of the legal uncertainty over an appeal to overturn his suspension.
Ugo Ehiogu, the former England defender who was a coach of the Tottenham Under-23s, died on Friday from cardiac arrest.
Paulo Henrique Ganso scored twice in his first start in more than three months to help Sevilla beat struggling Granada 2-0 in the Spanish league on Friday.