Tevin Coleman rushed for three touchdowns, Matt Ryan passed for two TDs, and Deion Jones returned an interception 90 yards for a score to help the Atlanta Falcons beat the winless New Orleans Saints 45-32 on Monday night.
Philadelphia continued its perfect start to the new NFL season by beating Pittsburgh 34-3 on Sunday, led by rookie quarterback Carson Wentz, who threw for 301 yards and two touchdowns, and a fierce defense.
Drew Brees hopes the world watches what happens in and around the Superdome on Monday night.
New England's third-string quarterback Jacoby Brissett had a touchdown run in his first NFL start as the Patriots cruised past Houston 27-0 on Thursday.
Ryan Matthews scored two touchdowns as the Philadelphia Eagles maintained their unbeaten start to the season with a 29-14 victory over the Chicago Bears at Soldier Field.
Sam Bradford had a Minnesota debut almost as dazzling as the Vikings' new US$1.1 billion stadium itself, completing 22 of 30 passes for 286 yards, two touchdowns and no turnovers to lead his team to a 17-14 victory over archrival Green Bay in the NFL on Sunday.
Matt Forte scored three touchdowns and Ryan Fitzpatrick finally solved Rex Ryan's defense, leading the New York Jets to a 37-31 victory over the Buffalo Bills on Thursday night.
When New Orleans Saints quarterback Drew Brees and New York Giants counterpart Eli Manning are playing in the same game it is personal, albeit in a friendly way.
A new Twitter app is coming to Xbox One, Apple TV and Amazon Fire TV, where viewers will be able to watch NFL games on Thursday nights.
Carlos Hyde ran for 88 yards and two touchdowns as the San Francisco 49ers spoiled the Rams' first game since moving back to Los Angeles with a 28-0 victory in the NFL on Monday.