Carolina held off New Orleans' fourth- quarter rally to beat the Saints 23-20 on Thursday in a game marred by injuries to key players.
Houston's Duke Catalon scored three touchdowns and the defense hurried and harassed Louisville quarterback Lamar Jackson all night to propel the Cougars to a stunning 36-10 victory on Thursday that dashed Cardinals' playoff hopes.
Eli Manning threw his third touchdown pass of the game on a fourth-down gamble by rookie coach Ben McAdoo as the New York Giants beat the Cincinnati Bengals 21-20 Monday night for their first four-game win streak since 2013.
Seattle took a small measure of revenge for the Super Bowl loss to New England two seasons back by making a strong goal-line stand to hang on for a 31-24 road victory against the Patriots on Sunday.
Michigan and Clemson both lost in stunning, 1-point upsets in college football on Saturday, while No. 1 Alabama remained undefeated as Jalen Hurts passed for career highs of 347 yards and four touchdowns.
The Baltimore Ravens gained sole possession of first place in the AFC North at the expense of the winless Cleveland Browns, who reached an historic low point in franchise history.
It's about time to start paying more attention to the AFC West-leading, Super Bowl champion-beating Oakland Raiders, from young, mistake-avoiding QB Derek Carr to pass-rusher extraordinaire Khalil Mack to twinkle-toed punter Marquette King.
NFL passing yardage leader Matt Ryan was nearly flawless again Thursday, as he threw for 344 yards, four touchdowns and no interceptions to help Atlanta beat Tampa Bay 43-28, tightening its grip on the NFC South lead.
Chicago quarterback Jay Cutler returned from a long injury absence to lead the Bears to an upset 20-10 win against Minnesota on Monday.
Dallas quarterback Dak Prescott threw a 5-yard touchdown pass to Jason Witten in overtime, giving the Cowboys their sixth straight win with a 29-23 victory over Philadelphia on Sunday.