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High-blood pressure genetic link discovered

WASHINGTON -- U.S. researchers have discovered a variant of a common gene linked to high-blood pressure, paving the way towards possible better treatments of the illness, a study said Monday. The gene, known as STK39, produces a protein which plays a role in helping the kidneys regulate the amount of salt inside a person's body.

“This discovery has great potential for enhancing our ability to tailor treatments to the individual — what we call personalized medicine — and to more effectively manage patients with hypertension,” said senior author Yen-Pei Christy Chang, from the University of Maryland School of Medicine.

“The STK39 gene is only one important piece of the puzzle,” she said. “We want to determine how people with different variations of this gene respond to diuretics and other medications, or to lifestyle changes, such as reducing the amount of salt in their diet.”

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