Updated Friday, February 29, 2008 0:00 am TWN, Bloomberg

Oculus treatment worked against diabetic foot ulcers

SAN FRANCISCO -- Oculus Innovative Sciences Inc., developer of the chlorine-based skin infection treatment Microcyn, said the drug was effective in treating diabetic foot ulcers, the leading cause of leg amputation in the U.S. Oculus’s therapy eliminated or reduced infection for three- fourths of patients after 10 days, compared with 57 percent who did that well on a standard saline rinse and levofloxacin, an antibiotic, the company said today in a statement. The benefit was sustained for at least 24 days for all patients on the Oculus drug, and all but one patient in the control group.

The results from the 66-patient study mark the first time the Microcyn technology has been tested directly against a standard treatment for infections. If the advantage can be confirmed in larger trials, it could offer a way to avoid overuse of antibiotics and provide a new option for treating diabetic foot ulcers, which lead to 80,000 amputations in the U.S. each year, Oculus said.

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