Marcello Lippi faces his biggest challenge as China coach, needing a win against South Korea to keep alive any hopes of qualifying for Russia 2018.
Lionel Messi scored his 40th and 41st goals in all competitions this season to lead Barcelona to a 4-2 victory over 10-man Valencia in the Spanish league on Sunday.
Joe Hart gifted Internazionale both of its goals but Torino managed to draw 2-2 in Serie A on Saturday and damage Inter's bid for a Champions League place.
Cristiano Ronaldo turned into Real Madrid's playmaker by setting up two goals to beat Athletic Bilbao 2-1 on Saturday and keep on track to reclaim the Spanish league title.
Kevin-Prince Boateng scored and forced the sending off of a Villarreal player to help Las Palmas win 1-0 at home in the Spanish league on Friday.
Manchester United's progress to the Europa League quarterfinals came at a cost after Paul Pogba hobbled off with a hamstring injury in the 1-0 win over Rostov on Thursday.
Midfielder Tiemoue Bakayoko's thumping header sent Monaco through to the Champions League quarterfinals as the home side beat Manchester City 3-1 on Wednesday to progress on the away goals rule in another pulsating match between two attack-minded sides.
Jan Oblak made one great stop. Then another. And another. All within a few seconds.
First, the Premier League title. Now, the Champions League quarterfinals.
Paulo Dybala's penalty set Juventus on its way to a 1-0 win over 10-man Porto on Tuesday and a place in the Champions League quarterfinals.